SCHEMBL9847459

SCHEMBL9847459

CCCCCCC(F)CC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.48
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.44
DNM1 Q05193 2/20 0.43
OPRM1 P35372 1/20 0.42
GPR84 Q9NQS5 3/20 0.39
FDPS P14324 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FFAR1 O14842 1/20 0.39
CES2 O00748 1/20 0.39
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8406367 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL8406872 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL14964664 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL30892701 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL5985987 0.97
SCHEMBL13127086 0.97
SCHEMBL24926247 0.88 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL19853017 0.88 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL10231127 0.88
SCHEMBL8173118 0.88 MAPT (0.52) MAPTTSHRTHRBLMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0438382-A1 Disubstituted aromatic dianhydrides and polyimides prepared therefrom CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed