SCHEMBL14964664

SCHEMBL14964664

CCCCCCCCCCC(F)CC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.48
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.44
DNM1 Q05193 2/20 0.43
OPRM1 P35372 1/20 0.42
GPR84 Q9NQS5 3/20 0.39
FDPS P14324 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FFAR1 O14842 1/20 0.39
CES2 O00748 1/20 0.39
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8406367 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL8406872 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL9847459 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL30892701 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL5985987 0.97
SCHEMBL13127086 0.97
SCHEMBL24926247 0.88 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL19853017 0.88 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL10231127 0.88
SCHEMBL8173118 0.88 MAPT (0.52) MAPTTSHRTHRBLMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9006472-B2 Methods for the synthesis of 13C labeled plasmalogen PHENOMENOME DISCOVERIES INC. (CA) 2015-04-14 US disclosed
US-20140323749-A1 METHODS FOR THE SYNTHESIS OF 13C LABELED PLASMALOGEN MED-LIFE DISCOVERIES LP (CA) 2014-10-30 US disclosed
WO-2013071412-A1 METHODS FOR THE SYNTHESIS OF 13C LABELED PLASMALOGEN PHENOMENOME DISCOVERIES INC. (CA) 2013-05-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140323749-A1 METHODS FOR THE SYNTHESIS OF 13C LABELED PLASMALOGEN PLPBP, SGMS2, PCCA MAPT 4453/4885TSHR 2733/4885THRB 2648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.