Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TK2 | O00142 | 4/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848561 | 1.00 | TK1 (0.76) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL10848568 | 1.00 | TK1 (0.76) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL11117681 | 1.00 | TK1 (0.76) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3410819 | 0.87 | TK1 (0.70) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL9847513 | 0.87 | TK1 (0.70) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3408681 | 0.86 | TK1 (0.79) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL10809607 | 0.86 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL10848178 | 0.86 | TK1 (1.00) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL10813778 | 0.85 | TK1 (0.67) | TK1CYP1A2CYP3A4TSHRBLM | |
| SCHEMBL3416032 | 0.83 | TK1 (0.74) | TK1CYP1A2CYP3A4TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418007-A2 | Cyclopentane derivatives | GLAXO GROUP LIMITED (GB) | 1991-03-20 | — | — | EP | disclosed |