Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081692 | 0.77 | KDM4E (0.42) | KDM4ECYP1A2NPC1CYP2D6CYP19A1 | |
| SCHEMBL9847537 | 0.77 | MYC (0.47) | KDM4ENPC1MYCPOLBSMN1; SMN2 | |
| SCHEMBL29883487 | 0.76 | KDM4E (0.41) | KDM4ECYP1A2NPC1CYP2D6CYP19A1 | |
| SCHEMBL8501158 | 0.75 | KDM4E (0.42) | KDM4ECYP1A2NPC1CYP2D6CYP19A1 | |
| SCHEMBL8896957 | 0.75 | ATM (0.37) | KDM4ECYP1A2NPC1CYP2D6CYP19A1 | |
| SCHEMBL3641432 | 0.73 | CYP1A2 (0.44) | KDM4ECYP1A2NPC1CYP2D6CYP19A1 | |
| SCHEMBL28515301 | 0.71 | CYP1A2 (0.42) | KDM4ECYP1A2NPC1CYP2D6CYP19A1 | |
| SCHEMBL454461 | 0.71 | CYP1A2 (0.42) | KDM4ECYP1A2NPC1CYP2D6CYP19A1 | |
| SCHEMBL29278701 | 0.71 | CYP1A2 (0.42) | KDM4ECYP1A2NPC1CYP2D6CYP19A1 | |
| SCHEMBL27396593 | 0.71 | CYP1A2 (0.42) | KDM4ECYP1A2NPC1CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411935-A2 | Copper radio sensitizers | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1991-02-06 | — | — | EP | disclosed |