Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896957 | 0.85 | ATM (0.37) | KDM4ECYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL9847559 | 0.82 | CYP11B1 (0.45) | KDM4ECYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL9847563 | 0.79 | ATM (0.39) | KDM4ECYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL30867783 | 0.77 | SMN1; SMN2 (0.51) | KDM4ECYP1A2MAPTCYP2C19CYP3A4 | |
| SCHEMBL7037994 | 0.77 | SMN1; SMN2 (0.51) | KDM4ECYP1A2MAPTCYP2C19CYP3A4 | |
| SCHEMBL5349206 | 0.77 | L3MBTL1 (0.61) | KDM4EMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL4101620 | 0.77 | L3MBTL1 (0.61) | KDM4EMAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL16081692 | 0.75 | KDM4E (0.42) | KDM4ECYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL9847539 | 0.75 | KDM4E (0.34) | KDM4ECYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL31703986 | 0.73 | CCR1 (0.46) | KDM4ECYP1A2MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772616-B1 | HYDROPHILIC METAL COMPLEXES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-12-15 | — | — | EP | disclosed |