Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 12/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330356 | 0.79 | HPN (0.47) | VCAM1MAPTHPNALOX15SIRT5 | |
| SCHEMBL9735154 | 0.79 | VCAM1 (0.48) | VCAM1MAPTHPNALOX15SIRT5 | |
| SCHEMBL9158690 | 0.76 | HPN (0.44) | VCAM1MAPTHPNALOX15SIRT5 | |
| SCHEMBL10961680 | 0.75 | MAPT (0.46) | VCAM1MAPTHPNALOX15SIRT5 | |
| SCHEMBL9852829 | 0.74 | HPN (0.55) | VCAM1MAPTHPNALOX15SIRT5 | |
| SCHEMBL9769341 | 0.74 | HPN (0.55) | VCAM1MAPTHPNALOX15SIRT5 | |
| SCHEMBL9165330 | 0.74 | HPN (0.55) | VCAM1MAPTHPNALOX15SIRT5 | |
| SCHEMBL9168124 | 0.74 | HPN (0.55) | VCAM1MAPTHPNALOX15SIRT5 | |
| SCHEMBL6438215 | 0.74 | VCAM1 (0.48) | VCAM1MAPTHPNALOX15SIRT5 | |
| SCHEMBL29638845 | 0.74 | VCAM1 (0.48) | VCAM1MAPTHPNALOX15SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414206-A2 | 2,4,6-Substituted phenol derivatives | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |