Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399393 | 0.88 | HTT (0.62) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8687542 | 0.86 | HTT (0.53) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9847773 | 0.86 | HTT (0.44) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9261996 | 0.84 | HTT (0.50) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL446113 | 0.82 | HTT (0.77) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29682980 | 0.82 | HTT (0.77) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8432658 | 0.81 | HTT (0.50) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8332488 | 0.80 | HTT (0.46) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8434168 | 0.80 | HTT (0.81) | HTTKDM4EALDH1A1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL9633469 | 0.80 | HTT (0.74) | HTTKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413415-A1 | Carboxylic acids and derivates thereof | The British Petroleum Company p.l.c. (GB) | 1991-02-20 | — | — | EP | disclosed |