Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9731685 | 0.83 | KCNH2 (0.71) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| Hydrochloric Acid SCHEMBL9731785 | 0.79 | KCNH2 (0.71) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9759926 | 0.78 | KCNH2 (0.58) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL7861253 | 0.68 | KCNH2 (0.78) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL7854083 | 0.68 | KCNH2 (0.72) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9760114 | 0.68 | NR3C2 (0.51) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9731859 | 0.67 | KCNH2 (0.56) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL10425925 | 0.67 | NPC1 (0.66) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9736383 | 0.67 | KCNH2 (0.50) | KCNH2CACNA1FCHRM2ACHEAGTR1 | |
| SCHEMBL9784162 | 0.66 | HTR1B (0.47) | NPC1RAB9ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431944-A2 | Benzofurazan derivatives having antiarrhythmic properties | MERCK & CO. INC. (US) | 1991-06-12 | — | — | EP | disclosed |