⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984818 | 1.00 | — | — | |
| SCHEMBL506587 | 1.00 | — | — | |
| SCHEMBL14856677 | 0.92 | — | — | |
| SCHEMBL19121731 | 0.81 | — | — | |
| SCHEMBL506921 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL2749956 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL1100486 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL124302 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL124301 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL1907225 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187311-A1 | STERICALLY HINDERED N-ALIPHATIC N-HETEROCYCLIC CARBENE CATALYSTS AND METHODS USING SAME | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-09-09 | — | — | WO | disclosed |
| US-8288602-B2 | Synthesis of substituted fluorene ligands | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2012-10-16 | — | — | US | disclosed |
| US-8288602-B2 | Synthesis of substituted fluorene ligands | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2012-10-16 | — | — | US | disclosed |
| US-8288602-B2 | Synthesis of substituted fluorene ligands | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2012-10-16 | — | — | US | disclosed |
| US-20110009683-A1 | SYNTHESIS OF SUBSTITUTED FLUORENE LIGANDS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-01-13 | — | — | US | disclosed |
| US-20110009683-A1 | SYNTHESIS OF SUBSTITUTED FLUORENE LIGANDS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-01-13 | — | — | US | disclosed |
| US-20110009683-A1 | SYNTHESIS OF SUBSTITUTED FLUORENE LIGANDS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-01-13 | — | — | US | disclosed |
| EP-1999091-B1 | SYNTHESIS OF SUBSTITUTED FLUORENES | TOTAL PETROCHEMICALS RES FELUY (BE) | 2010-08-04 | — | — | EP | disclosed |