Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486709 | 0.82 | MTNR1A (0.51) | MTNR1AMTNR1BCYP19A1AKR1C1MEN1 | |
| SCHEMBL294670 | 0.82 | MTNR1A (0.47) | MTNR1AMTNR1BCYP19A1AKR1C1MEN1 | |
| SCHEMBL5157146 | 0.79 | MTNR1A (0.51) | MTNR1AMTNR1BCYP19A1AKR1C1MEN1 | |
| SCHEMBL8873211 | 0.78 | MTNR1A (0.44) | MTNR1AMTNR1BCYP19A1AKR1C1MEN1 | |
| SCHEMBL8872181 | 0.78 | MTNR1A (0.44) | MTNR1AMTNR1BCYP19A1AKR1C1MEN1 | |
| SCHEMBL8872191 | 0.78 | MTNR1A (0.44) | MTNR1AMTNR1BCYP19A1AKR1C1MEN1 | |
| SCHEMBL3577074 | 0.77 | HDAC3 (0.53) | MTNR1AMTNR1BCYP19A1AKR1C1MEN1 | |
| SCHEMBL3577068 | 0.77 | HDAC3 (0.53) | MTNR1AMTNR1BCYP19A1AKR1C1MEN1 | |
| SCHEMBL3577072 | 0.77 | HDAC3 (0.53) | MTNR1AMTNR1BCYP19A1AKR1C1MEN1 | |
| SCHEMBL6673216 | 0.77 | CYP19A1 (0.43) | MTNR1AMTNR1BCYP19A1AKR1C1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405713-A1 | Polymerization of liquid crystalline monomers | EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) | 1991-01-02 | — | — | EP | disclosed |