Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | REN | P00797 | 4/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451867 | 0.83 | MME (0.54) | MMELTA4HACEANPEPECE1 | |
| SCHEMBL7368655 | 0.83 | MME (0.54) | MMELTA4HACEANPEPECE1 | |
| SCHEMBL6451863 | 0.83 | MME (0.54) | MMELTA4HACEANPEPECE1 | |
| SCHEMBL7330319 | 0.80 | MAPK1 (0.58) | MMELTA4HREN | |
| SCHEMBL6443861 | 0.79 | MME (0.67) | MMELTA4HRENECE1 | |
| SCHEMBL6443855 | 0.79 | MME (0.67) | MMELTA4HRENECE1 | |
| SCHEMBL7378502 | 0.77 | HDAC3 (0.53) | MMELTA4H | |
| SCHEMBL7163321 | 0.77 | CYP1A2 (0.59) | MMEANPEP | |
| SCHEMBL7269232 | 0.77 | CYP1A2 (0.59) | MMEANPEP | |
| SCHEMBL7277365 | 0.77 | CYP1A2 (0.59) | MMEANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428849-A2 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | disclosed |