Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.54 |
| ▸ | ECE1 | P42892 | 5/20 | 0.53 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6451867 | 1.00 | MME (0.54) | MMEECE1LTA4HACEANPEP | |
| SCHEMBL6451863 | 1.00 | MME (0.54) | MMEECE1LTA4HACEANPEP | |
| SCHEMBL10439584 | 0.83 | HRH4 (0.46) | MMEECE1ACEALDH1A1 | |
| SCHEMBL9848463 | 0.83 | MME (0.43) | MMEECE1LTA4HACEANPEP | |
| SCHEMBL6443855 | 0.83 | MME (0.67) | MMEECE1LTA4H | |
| SCHEMBL6443861 | 0.83 | MME (0.67) | MMEECE1LTA4H | |
| SCHEMBL7290825 | 0.83 | REN (0.41) | MMEECE1LTA4H | |
| SCHEMBL7330319 | 0.81 | MAPK1 (0.58) | MMELTA4H | |
| SCHEMBL7163321 | 0.81 | CYP1A2 (0.59) | MMEANPEP | |
| SCHEMBL7269232 | 0.81 | CYP1A2 (0.59) | MMEANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354522-A1 | Use of alpha-aminoboronic acid derivatives in prevention and treatement of viral diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-14 | — | — | EP | disclosed |
| EP-0315574-A2 | Renin inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-10 | — | — | EP | disclosed |