Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CASR | P41180 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092329 | 0.84 | TDP1 (0.59) | TDP1MEN1KMT2AL3MBTL1CASR | |
| SCHEMBL22445577 | 0.82 | TDP1 (0.58) | TDP1MEN1KMT2AL3MBTL1CASR | |
| SCHEMBL12493466 | 0.82 | TDP1 (0.58) | TDP1MEN1KMT2AL3MBTL1CASR | |
| SCHEMBL4885737 | 0.79 | TDP1 (0.54) | TDP1MEN1KMT2ACASRHTT | |
| SCHEMBL4885725 | 0.79 | TDP1 (0.54) | TDP1MEN1KMT2ACASRHTT | |
| SCHEMBL4887164 | 0.79 | TDP1 (0.54) | TDP1MEN1KMT2ACASRHTT | |
| SCHEMBL4846798 | 0.78 | TDP1 (0.53) | TDP1MEN1KMT2ACASRHTT | |
| SCHEMBL27826995 | 0.78 | TDP1 (0.56) | TDP1MEN1KMT2AL3MBTL1CASR | |
| SCHEMBL6552029 | 0.78 | TDP1 (0.56) | TDP1MEN1KMT2AL3MBTL1CASR | |
| SCHEMBL6142841 | 0.77 | CASR (0.75) | TDP1MEN1KMT2AL3MBTL1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |