Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.63 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.55 |
| ▸ | UGCG | Q16739 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716121 | 1.00 | ASAH1 (0.63) | ASAH1ALDH1A1ACER2CERT1DNM1 | |
| SCHEMBL10844236 | 0.89 | ASAH1 (0.60) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL28217435 | 0.88 | ASAH1 (0.66) | ASAH1ALDH1A1ACER2CERT1UGCG | |
| SCHEMBL8338663 | 0.87 | ASAH1 (0.68) | ASAH1ALDH1A1ACER2CERT1 | |
| SCHEMBL6570067 | 0.87 | ASAH1 (0.68) | ASAH1ALDH1A1ACER2CERT1 | |
| SCHEMBL7769012 | 0.87 | ASAH1 (0.68) | ASAH1ALDH1A1ACER2CERT1 | |
| SCHEMBL7769010 | 0.87 | ASAH1 (0.68) | ASAH1ALDH1A1ACER2CERT1 | |
| SCHEMBL27369417 | 0.86 | ITGB3 (0.49) | ASAH1ALDH1A1ACER2 | |
| SCHEMBL27758299 | 0.84 | ASAH1 (0.60) | ASAH1ALDH1A1ACER2CERT1 | |
| SCHEMBL9716117 | 0.83 | ASAH1 (0.61) | ASAH1ALDH1A1ACER2CERT1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |