Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593026 | 0.75 | ALDH1A1 (0.60) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL27904488 | 0.75 | ADORA2A (0.47) | ALDH1A1MAPTL3MBTL1MAPK1MKNK1 | |
| Hydrochloric Acid SCHEMBL28376383 | 0.73 | ADORA2A (0.46) | ALDH1A1MAPTL3MBTL1MAPK1MKNK1 | |
| SCHEMBL14844681 | 0.72 | ADORA2A (0.47) | KMT2AMEN1MKNK1MKNK2CDC7 | |
| SCHEMBL29097661 | 0.72 | MKNK1 (0.43) | MAPK1MKNK1MKNK2CDC7OGA | |
| Hydrochloric Acid SCHEMBL28374859 | 0.72 | ADORA2A (0.45) | ALDH1A1MAPTL3MBTL1MAPK1MKNK1 | |
| Hydrochloric Acid SCHEMBL28375706 | 0.72 | ADORA2A (0.45) | ALDH1A1MAPTL3MBTL1MAPK1MKNK1 | |
| SCHEMBL3262365 | 0.71 | MAPK1 (0.44) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL18803631 | 0.71 | MKNK1 (0.60) | MAPTMKNK1MKNK2CDC7 | |
| SCHEMBL21568429 | 0.69 | GRIN2D (0.47) | MKNK1MKNK2KDM1APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135642-A | Inhibitors of mutant forms of EGFR | 缆图药品公司 | 2022-09-30 | — | — | CN | disclosed |
| EP-0417584-A2 | N-substituted-4-pyrimidinamines and -pyrimidindiamines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-03-20 | — | — | EP | disclosed |