SCHEMBL9848550

SCHEMBL9848550

CCCCc1ccc(Nc2ccc(C)c3c2C2(OC3=O)c3ccccc3Oc3ccccc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ATM Q13315 2/20 0.33
HPGD P15428 2/20 0.33
KMT2A Q03164 2/20 0.32
TP53 P04637 1/20 0.32
XBP1 P17861 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
MEN1 O00255 1/20 0.32
DGAT1 O75907 1/20 0.32
UNG P13051 2/20 0.31
F13A1 P00488 1/20 0.31
TGM2 P21980 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3969541 0.86 UNG (0.36) POLBMAPTHTTALDH1A1CRHBP
SCHEMBL11023595 0.85 NPC1 (0.39) POLBMAPTHTTALDH1A1NPSR1
SCHEMBL3974160 0.85 ALDH1A1 (0.39) POLBMAPTHTTALDH1A1NPSR1
SCHEMBL10589556 0.85 MAPT (0.32) POLBMAPTHTTALDH1A1CRHBP
SCHEMBL7771612 0.82 UNG (0.39) POLBMAPTHTTALDH1A1CRHBP
SCHEMBL10580661 0.82 MEN1 (0.34) MAPTHTTALDH1A1NPSR1HPGD
SCHEMBL5184715 0.81 POLB (0.40) POLBMAPTHTTALDH1A1CRHBP
SCHEMBL6535406 0.79 NPSR1 (0.38) MAPTHTTALDH1A1NPSR1HPGD
SCHEMBL10640227 0.79 ALDH1A1 (0.36) POLBMAPTHTTALDH1A1HPGD
SCHEMBL9801536 0.78 ALDH1A1 (0.35) MAPTHTTALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0405363-A2 Heat-sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1991-01-02 EP disclosed