Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5070878 | 0.79 | DHFR (0.56) | SCN2ADHFRALDH1A1TSHRNPC1 | |
| SCHEMBL9848562 | 0.77 | SCN9A (0.57) | SCN9ASCN2ACYP2D6MAOAMAPK1 | |
| SCHEMBL5072690 | 0.76 | NCOA1 (0.41) | CYP2D6DHFRALDH1A1TSHRCCNA2 | |
| SCHEMBL978226 | 0.71 | SCN9A (0.61) | SCN9ASCN2ACYP2D6MAOAMAPK1 | |
| SCHEMBL30413401 | 0.71 | SCN9A (0.61) | SCN9ASCN2ACYP2D6MAOAMAPK1 | |
| SCHEMBL8903239 | 0.70 | SCN9A (0.55) | SCN9ASCN2ACYP2D6MAOAMAPK1 | |
| SCHEMBL7377151 | 0.69 | SCN2A (0.47) | SCN9ASCN2ASCN5ASCN3ASCN10A | |
| SCHEMBL9848578 | 0.69 | SCN9A (0.54) | SCN9ASCN2ACYP2D6MAOAMAPK1 | |
| SCHEMBL6374569 | 0.69 | SCN9A (0.58) | SCN9ASCN2ACYP2D6MAOAMAPK1 | |
| SCHEMBL16854426 | 0.69 | SCN9A (0.58) | SCN9ASCN2ACYP2D6MAOAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459829-A1 | Pharmacologically active CNS compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |