Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 11/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848662 | 0.90 | MME (0.39) | MMEBACE1BACE2LTA4HCTSD | |
| SCHEMBL9848677 | 0.89 | OPRD1 (0.45) | BACE1BACE2 | |
| SCHEMBL9848643 | 0.89 | BACE1 (0.42) | BACE1BACE2CTSD | |
| SCHEMBL9848637 | 0.84 | OPRD1 (0.36) | BACE1BACE2FNTAFNTB | |
| SCHEMBL9848661 | 0.83 | FNTA (0.42) | BACE1BACE2FNTAFNTB | |
| SCHEMBL9848660 | 0.80 | OPRD1 (0.45) | BACE1BACE2CTSD | |
| SCHEMBL9848673 | 0.78 | BACE1 (0.53) | MMEBACE1BACE2LTA4HCTSD | |
| SCHEMBL9848683 | 0.70 | BACE1 (0.35) | BACE1CTSD | |
| SCHEMBL17305518 | 0.70 | BACE1 (0.62) | BACE1BACE2CTSDFNTAFNTB | |
| SCHEMBL29500570 | 0.70 | BACE1 (0.56) | MMEBACE1BACE2CTSDFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |