Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10982252 | 0.89 | CYP4F2 (0.50) | PPARAF2RL1CYP4F2CYP4A11KMT2A | |
| SCHEMBL2722383 | 0.87 | F2RL1 (0.60) | F2RL1LMNAL3MBTL1FFAR1MAPT | |
| SCHEMBL29059895 | 0.84 | ELANE (0.57) | PPARAF2RL1CYP4F2CYP4A11KMT2A | |
| SCHEMBL23772470 | 0.84 | TDP1 (0.53) | PPARAPPARGCYP4F2CYP4A11LMNA | |
| SCHEMBL29059946 | 0.84 | SLC5A1 (0.52) | CYP4F2CYP4A11ACACBADRB2ADRB1 | |
| SCHEMBL2789562 | 0.83 | FFAR1 (0.59) | PPARALMNAL3MBTL1FFAR1 | |
| SCHEMBL10389748 | 0.83 | ALDH1A1 (0.53) | PPARAF2RL1PPARGKMT2AACACB | |
| SCHEMBL7420345 | 0.83 | CYP4F2 (0.49) | CYP4F2CYP4A11KMT2ALMNAL3MBTL1 | |
| SCHEMBL9784096 | 0.83 | ACACB (0.46) | PPARAPPARGCYP4F2CYP4A11KMT2A | |
| SCHEMBL1587126 | 0.83 | MEN1 (0.45) | CYP4F2CYP4A11KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523493-B1 | NOVEL TUBULYSIN ANALOGUES | DOEMLING ALEXANDER (DE) | 2013-09-04 | — | — | EP | disclosed |
| EP-1511751-B1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AS ANTIVIRAL AGENTS | NEOGENESIS PHARMACEUTICALS INC (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007044410-A1 | PYRAZOLO [1,5-A] PYRIMIDINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |
| EP-0438873-A1 | Inhibitor of ribonucleotide reductase of herpes viruses | MERCK & CO. INC. (US) | 1991-07-31 | — | — | EP | disclosed |