Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848804 | 1.00 | EPHX1 (0.53) | EPHX1IDO1ACEGAAPPARG | |
| SCHEMBL918775 | 0.88 | KIF11 (0.56) | EPHX1IDO1ACEGAAPPARG | |
| SCHEMBL530442 | 0.88 | KIF11 (0.56) | EPHX1IDO1ACEGAAPPARG | |
| SCHEMBL530443 | 0.88 | KIF11 (0.56) | EPHX1IDO1ACEGAAPPARG | |
| SCHEMBL1277636 | 0.87 | KIF11 (0.55) | EPHX1IDO1ACEGAAPPARG | |
| SCHEMBL1277641 | 0.87 | KIF11 (0.55) | EPHX1IDO1ACEGAAPPARG | |
| Hydrochloric Acid SCHEMBL6961108 | 0.85 | KIF11 (0.54) | EPHX1IDO1ACEGAAPPARG | |
| SCHEMBL3416831 | 0.84 | ACE (0.46) | EPHX1IDO1ACEGAAPPARG | |
| Hydrochloric Acid SCHEMBL3416827 | 0.83 | IDO1 (0.46) | EPHX1IDO1ACEGAAPPARG | |
| Hydrochloric Acid SCHEMBL3416832 | 0.83 | IDO1 (0.46) | EPHX1IDO1ACEGAAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459730-A2 | Anti-tumour compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |