Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.46 |
| ▸ | CTSS | P25774 | 7/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31407522 | 0.84 | ACE (0.55) | CTSKCTSSCTSLCTSBACE | |
| SCHEMBL31407438 | 0.84 | ACE (0.55) | CTSKCTSSCTSLCTSBACE | |
| SCHEMBL7464875 | 0.81 | ATM (0.47) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL7464877 | 0.81 | ATM (0.47) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL10886356 | 0.79 | CTSK (0.52) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL21193996 | 0.79 | CTSK (0.52) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL118081 | 0.79 | CTSK (0.54) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL3755737 | 0.79 | CTSK (0.54) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL14923573 | 0.79 | CTSK (0.54) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL19517266 | 0.77 | CTSK (0.56) | CTSKCTSSATMCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459730-A2 | Anti-tumour compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |