Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22887206 | 0.89 | SMN1; SMN2 (0.70) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL26975749 | 0.87 | NR1H4 (0.67) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL11648261 | 0.84 | NPC1 (0.68) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL9848853 | 0.79 | MAOB (0.61) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL28343739 | 0.79 | KMT2A (0.56) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL4436642 | 0.78 | KCNK3 (0.77) | NPC1SMN1; SMN2KMT2AMAPTKDM4E | |
| SCHEMBL28519972 | 0.77 | ESR1 (0.73) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL27744379 | 0.77 | ESR1 (0.73) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL3592038 | 0.76 | RAB9A (0.78) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL29800540 | 0.76 | NPC1 (1.00) | NPC1SMN1; SMN2KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410471-A2 | 2-alkyl-4-methoxy-5-aminophenol or salt thereof, or 2-alkyl-4-methoxy-5-substituted aminophenol or salt thereof, and dyeing composition for keratin fibers comprising the same | Kao Corporation (JP) | 1991-01-30 | — | — | EP | disclosed |