SCHEMBL9848860

SCHEMBL9848860

CC(=O)NCc1ccccc1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.57
HIF1A Q16665 1/20 0.51
SETDB1 Q15047 1/20 0.50
FOLH1 Q04609 1/20 0.50
HPGD P15428 5/20 0.49
KMT2A Q03164 2/20 0.49
APEX1 P27695 1/20 0.47
ALDH1A1 P00352 3/20 0.46
ALOX15 P16050 1/20 0.46
MTNR1A P48039 1/20 0.46
CLCN2 P51788 1/20 0.46
TSHR P16473 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
BRD4 O60885 1/20 0.46
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14204990 0.84 SETDB1 (0.59) SETDB1HPGDKMT2AALDH1A1MTNR1A
SCHEMBL28984805 0.84 SETDB1 (0.49) HTTSETDB1HPGDALDH1A1MTNR1A
SCHEMBL27989127 0.82 ALDH1A1 (0.61) HIF1ASETDB1HPGDKMT2AALDH1A1
SCHEMBL14055032 0.82 HTT (0.54) HTTHIF1AFOLH1HPGDKMT2A
SCHEMBL12700344 0.81 HTT (0.76) HTTHIF1AHPGDKMT2AAPEX1
SCHEMBL2652549 0.81 HTT (0.53) HTTHIF1AFOLH1HPGDKMT2A
SCHEMBL3130427 0.81 HIF1A (0.54) HTTHIF1AFOLH1HPGDKMT2A
SCHEMBL27378833 0.81 SETDB1 (0.47) HTTSETDB1HPGDALDH1A1MTNR1A
SCHEMBL14782975 0.81 HTT (0.53) HTTHIF1AFOLH1HPGDKMT2A
SCHEMBL6141162 0.81 HTT (0.53) HTTHIF1AFOLH1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114007734-A Method for preparing capsules 宝洁公司 2022-02-01 CN disclosed
CN-113660926-A Capsule 宝洁公司 2021-11-16 CN disclosed
CN-113631695-A Capsule 宝洁公司 2021-11-09 CN disclosed
CN-102883803-B Delivery particles THE PROCTER & GAMBLE CO. (US) 2016-04-27 CN disclosed
CN-103622842-A Delivery particles PROCTER & GAMBLE 2014-03-12 CN disclosed
CN-102883803-A Delivery particles PROCTER & GAMBLE 2013-01-16 CN disclosed
EP-0414287-A1 Particulate contrast media NYCOMED IMAGING AS (NO) 1991-02-27 EP disclosed
EP-0414288-A1 Contrast media NYCOMED IMAGING AS (NO) 1991-02-27 EP disclosed