Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.55 |
| ▸ | FCER2 | P06734 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 7/20 | 0.51 |
| ▸ | CPA1 | P15085 | 7/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069033 | 0.85 | MME (0.63) | MMEFCER2ACECPA1ACE2 | |
| SCHEMBL6199749 | 0.85 | CYP1A2 (0.58) | MME | |
| SCHEMBL6199752 | 0.85 | CYP1A2 (0.58) | MME | |
| SCHEMBL9069196 | 0.85 | MME (0.63) | MMEFCER2ACECPA1ACE2 | |
| SCHEMBL7416436 | 0.84 | MME (0.51) | MMEFCER2ACECPA1ACE2 | |
| SCHEMBL9068808 | 0.81 | MMP2 (0.65) | MMEFCER2ACECPA1ACE2 | |
| SCHEMBL6169551 | 0.81 | MME (0.60) | MMEACECPA1ACE2 | |
| SCHEMBL6169549 | 0.81 | MME (0.60) | MMEACECPA1ACE2 | |
| SCHEMBL5916397 | 0.80 | MME (0.55) | MMEACE | |
| SCHEMBL6172440 | 0.80 | MME (0.68) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449523-A1 | Mercapto- or acylthio-trifluoromethyl amide derivatives and their use | E.R. SQUIBB & SONS, INC. (US) | 1991-10-02 | — | — | EP | disclosed |