Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15060595 | 0.84 | MAPT (0.53) | SMN1; SMN2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL203816 | 0.81 | CYP19A1 (0.56) | SMN1; SMN2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL13017080 | 0.81 | HPSE (0.48) | SMN1; SMN2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL3772613 | 0.80 | AR (0.54) | SMN1; SMN2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL202654 | 0.77 | MEN1 (0.60) | SMN1; SMN2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL29519297 | 0.77 | AMY1A (0.61) | SMN1; SMN2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL129994 | 0.77 | AMY1A (0.61) | SMN1; SMN2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL14378910 | 0.76 | KDM4E (0.75) | SMN1; SMN2KDM4ENPC1CRHBPRAB9A | |
| Bromide SCHEMBL8355183 | 0.76 | AMY1A (0.59) | SMN1; SMN2KDM4ENPC1CRHBPRAB9A | |
| SCHEMBL8698255 | 0.76 | MAPT (0.53) | SMN1; SMN2KDM4ENPC1CRHBPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411718-A2 | Thiazole derivatives, their preparation and their use as fungicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-02-06 | — | — | EP | disclosed |