Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849156 | 0.86 | ALDH1A1 (0.55) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL10624673 | 0.85 | ALDH1A1 (0.65) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL16001113 | 0.84 | ALDH1A1 (0.67) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL5860010 | 0.84 | ALDH1A1 (0.67) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL1686141 | 0.84 | ALDH1A1 (0.67) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL23004849 | 0.84 | ALDH1A1 (0.67) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL4705070 | 0.84 | ALDH1A1 (0.67) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL10770311 | 0.83 | ALDH1A1 (0.62) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL27394284 | 0.82 | ALDH1A1 (0.64) | ALDH1A1RECQLMAPK1PKMKDM4E | |
| SCHEMBL4063597 | 0.81 | ALDH1A1 (0.62) | ALDH1A1RECQLMAPK1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421436-A2 | Substituted carboxytetrahydroisoquinolines and derivatives thereof having pharmaceutical activity | WARNER-LAMBERT COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |