Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GCG | P01275 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16984472 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL28880719 | 0.80 | NPC1 (0.60) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT | |
| Acetic Acid SCHEMBL9849558 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| Potassium SCHEMBL30101822 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL11712509 | 0.77 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL31098995 | 0.77 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL22545323 | 0.75 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL7054045 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL6535305 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1HPGDPOLBMAPT | |
| SCHEMBL9077089 | 0.72 | MAPK1 (0.83) | KDM4EALDH1A1SMN1; SMN2MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446604-A2 | Pyridine and related aza heterocycle derivatives as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |