Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11712509 | 1.00 | KDM4E (0.65) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL1577669 | 0.85 | ALDH1A1 (0.63) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL837692 | 0.83 | MEN1 (0.75) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL24249663 | 0.82 | KDM4E (0.71) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL4272819 | 0.80 | SLC2A1 (0.56) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL1702216 | 0.79 | KDM4E (0.59) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL837706 | 0.79 | MEN1 (0.74) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL16984472 | 0.79 | KDM4E (0.55) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL25894269 | 0.79 | KMT2A (0.56) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL11916198 | 0.78 | CYP1A2 (0.49) | KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390755-B | Heteroaryl method for amine | 中国科学院理化技术研究所 | 2024-08-02 | — | — | CN | claimed |