SCHEMBL9849600

SCHEMBL9849600

CC(Sc1ccccc1F)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
NPSR1 Q6W5P4 2/20 0.49
PRNP P04156 2/20 0.46
KDM4E B2RXH2 2/20 0.46
MAP2K7 O14733 1/20 0.46
ELANE P08246 1/20 0.46
CDC25A P30304 1/20 0.46
CDC25B P30305 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPK10 P53779 1/20 0.46
POLB P06746 2/20 0.44
LMNA P02545 3/20 0.42
SLC22A12 Q96S37 1/20 0.40
PTGS2 P35354 3/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
PTGS1 P23219 3/20 0.39
FABP2 P12104 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13603779 0.88 RXFP1 (0.54) RXFP1SMN1; SMN2NPSR1PRNPKDM4E
SCHEMBL11600500 0.81 PPARG (0.39) SMN1; SMN2ALDH1A1POLBLMNAMEN1
SCHEMBL11517389 0.81 RXFP1 (0.50) RXFP1SMN1; SMN2NPSR1PRNPKDM4E
SCHEMBL11522249 0.79 RXFP1 (0.47) RXFP1SMN1; SMN2NPSR1PRNPKDM4E
SCHEMBL9849304 0.79 RXFP1 (0.49) RXFP1SMN1; SMN2NPSR1PRNPKDM4E
SCHEMBL1849376 0.79 RXFP1 (0.47) RXFP1SMN1; SMN2NPSR1PRNPKDM4E
SCHEMBL10589041 0.79 NPSR1 (0.49) RXFP1SMN1; SMN2NPSR1PRNPKDM4E
SCHEMBL10745516 0.79 POLB (0.63) RXFP1SMN1; SMN2NPSR1PRNPKDM4E
SCHEMBL19361748 0.77 POLB (0.39) SMN1; SMN2MAP2K7CDC25ACDC25BALDH1A1
SCHEMBL9849368 0.76 SMN1; SMN2 (0.48) SMN1; SMN2POLBLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0454459-A2 Sulfonylalkanoic acid amide derivatives TAISHO PHARMACEUTICAL CO. LTD (JP) 1991-10-30 EP disclosed