Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849374 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL9849600 | 0.76 | RXFP1 (0.49) | SMN1; SMN2KMT2AMEN1HPGDPOLB | |
| SCHEMBL9849537 | 0.70 | KMT2A (0.46) | KMT2AMEN1RAB9ANPC1KDM1A | |
| SCHEMBL31582251 | 0.68 | LMNA (0.56) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL25464181 | 0.67 | GRM7 (0.73) | KMT2AMEN1RAB9AKDM1AHPGD | |
| SCHEMBL25464184 | 0.67 | GRM7 (0.73) | KMT2AMEN1RAB9AKDM1AHPGD | |
| SCHEMBL8225263 | 0.67 | GRM7 (0.73) | KMT2AMEN1RAB9AKDM1AHPGD | |
| SCHEMBL25941164 | 0.67 | CKS1B (0.49) | SMN1; SMN2RAB9APOLBLMNA | |
| SCHEMBL19361748 | 0.66 | POLB (0.39) | SMN1; SMN2RAB9ANPC1POLBLMNA | |
| SCHEMBL31582397 | 0.66 | RAB9A (0.50) | SMN1; SMN2KMT2AMEN1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454459-A2 | Sulfonylalkanoic acid amide derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1991-10-30 | — | — | EP | disclosed |