Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17891235 | 0.83 | KMT2A (0.51) | KMT2AHPGDITGB2ICAM1ITGAL | |
| SCHEMBL27861547 | 0.81 | KMT2A (0.39) | KMT2AALOX15CYP2C9HPGDCYP2C19 | |
| SCHEMBL11995109 | 0.79 | ABCG2 (0.42) | KMT2AALOX15CYP2C9HPGDCYP2C19 | |
| SCHEMBL9134742 | 0.76 | CYP2C9 (0.40) | KMT2AALOX15CYP2C9HPGDCYP2C19 | |
| SCHEMBL27672516 | 0.76 | HPGD (0.40) | KMT2AALOX15CYP2C9HPGDCYP2C19 | |
| SCHEMBL9378956 | 0.73 | TSHR (0.59) | KMT2ATSHRGAAMAPTMEN1 | |
| SCHEMBL28171665 | 0.73 | SIRT1 (0.51) | ALOX15CYP2C9HPGDCYP2C19HIF1A | |
| SCHEMBL27595430 | 0.73 | HPGD (0.39) | KMT2AALOX15CYP2C9HPGDCYP2C19 | |
| SCHEMBL31547779 | 0.73 | CYP2C9 (0.39) | KMT2AALOX15CYP2C9HPGDCYP2C19 | |
| SCHEMBL21094560 | 0.71 | HSD17B10 (0.38) | KMT2AALOX15CYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427484-A1 | Novel benzoxazolone compounds and the use thereof as microbicides | ROHM AND HAAS COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |