Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.44 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295696 | 0.85 | NSD2 (0.50) | NSD2HSP90AA1HKDC1TLR9ELANE | |
| SCHEMBL16295956 | 0.82 | NSD2 (0.50) | NSD2HSP90AA1HKDC1TLR9ELANE | |
| SCHEMBL17797112 | 0.81 | NSD2 (0.49) | NSD2HSP90AA1HKDC1TLR9ELANE | |
| SCHEMBL16296103 | 0.78 | HSP90AA1 (0.51) | NSD2HSP90AA1HKDC1TLR9ELANE | |
| SCHEMBL9849832 | 0.78 | HKDC1 (0.74) | NSD2HSP90AA1HKDC1TLR9ELANE | |
| SCHEMBL17797122 | 0.77 | HSP90AA1 (0.50) | NSD2HSP90AA1HKDC1TLR9MAPT | |
| SCHEMBL16295208 | 0.75 | TLR9 (0.51) | NSD2HSP90AA1HKDC1TLR9MAPT | |
| SCHEMBL16572509 | 0.73 | TLR9 (0.45) | NSD2HSP90AA1HKDC1TLR9MAPT | |
| SCHEMBL16296018 | 0.73 | HSP90AA1 (0.53) | NSD2HSP90AA1HKDC1TLR9MAPT | |
| SCHEMBL16295762 | 0.72 | NSD2 (0.49) | NSD2HSP90AA1HKDC1TLR9ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410172-A2 | 2-Halogeno-3-phenoxy-1,4-naphthoquinone derivatives | BAYER AG (DE) | 1991-01-30 | — | — | EP | disclosed |