⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28072549 | 0.97 | — | — | |
| SCHEMBL8405995 | 0.81 | ALDH1A1 (0.48) | — | |
| SCHEMBL425069 | 0.80 | — | — | |
| SCHEMBL9276 | 0.79 | — | — | |
| SCHEMBL509780 | 0.78 | ALDH1A1 (0.43) | — | |
| SCHEMBL29116687 | 0.78 | MGAM (0.36) | — | |
| Methylene Chloride SCHEMBL15537233 | 0.78 | ALDH1A1 (0.50) | — | |
| SCHEMBL6815785 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL29222512 | 0.77 | — | — | |
| SCHEMBL27276810 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115501204-A | Preparation method of hyaluronic acid nano drug delivery system for cascade drug delivery | 河北工业大学 | 2022-12-23 | — | — | CN | claimed |
| CN-101314591-B | Novel pyrazoles highly-selective marijuana acceptor-1antagon and/or reversed activation agent | SHANGHAI SUN SAIL PHARMACEUTICAL SCIENCE & TECHNOLOGY CO LTD | 2010-09-29 | — | — | CN | claimed |
| CN-101314591-A | Novel pyrazoles highly-selective marijuana acceptor-1antagon and/or reversed activation agent | SHANGHAI SUN SAIL PHARMACEUTIC (CN) | 2008-12-03 | — | — | CN | claimed |
| JP-63012344-A | — | — | None | — | — | JP | disclosed |
| CN-115501204-A | Preparation method of hyaluronic acid nano drug delivery system for cascade drug delivery | 河北工业大学 | 2022-12-23 | — | — | CN | disclosed |
| EP-3737665-A1 | PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF | XW Laboratories Inc. (KY) | 2020-11-18 | — | — | EP | disclosed |
| WO-2019137381-A1 | PRODRUGS OF KETAMINE, COMPOSITIONS AND USES THEREOF | XW LABORATORIES, INC. (CN) | 2019-07-18 | — | — | WO | disclosed |
| CN-109499618-A | A kind of catalyst and the preparation method and application thereof being used to prepare benzoyl formic acid and its ester type compound | 陕西延长石油（集团）有限责任公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-103502342-B | For the 5H-furans-2-ketone derivatives of stability of organic materials | BASF SE (DE) | 2016-03-09 | — | — | CN | disclosed |
| CN-102264740-B | Pyrrolo [ 1, 2 -b] pyridazine derivatives and their use as hif modulators | FIBROGEN, INC. (US) | 2014-10-15 | — | — | CN | disclosed |
| CN-104066720-A | Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an SO2-containing group as vanilloid receptor ligands | GRUENENTHAL GMBH | 2014-09-24 | — | — | CN | disclosed |
| CN-1056836-C | 3,5-disubstituted and 3,4,5-trisubstituted 2-isoxazolines and isoxazoles, process for preparing same and their use as medicaments | HOECHST AG (DE) | 2000-09-27 | — | — | CN | disclosed |
| CN-1155539-A | Endothelin receptor antagonists | MERCK PATENT GMBH (DE) | 1997-07-30 | — | — | CN | disclosed |
| CN-1143956-A | 3,5-disubstituted and 3,4,5-trisubstituted 2-isoxazolines and isoxazoles, process for preparing same and their use as medicaments | HOECHST AG (DE) | 1997-02-26 | — | — | CN | disclosed |
| CN-1081437-A | Antiulcer pyridine oxygen derivative, their preparation method and purposes | SANKYO CO (JP) | 1994-02-02 | — | — | CN | disclosed |
| EP-0292230-B1 | PHENYLACETIC ACID DERIVATIVES AND THEIR USE IN THE PREPARATION OF CEPHALOSPORIN ANTIBIOTICS | AJINOMOTO CO., INC. (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0292230-A2 | Phenylacetic acid derivatives and their use in the preparation of cephalosporin antibiotics | AJINOMOTO CO., INC. (JP) | 1988-11-23 | — | — | EP | disclosed |
| JP-S6312344-A | REFORMED POROUS MATERIAL | AGENCY OF IND SCIENCE & TECHNOL | 1988-01-19 | — | — | JP | disclosed |
| US-4089865-A | Certain thiazole compounds | SYNTEX (U.S.A.) INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4001421-A | THIAZOLE CARDIOVASCULAR AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-04 | — | — | US | disclosed |