Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 2/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850217 | 1.00 | LMNA (0.51) | LMNANT5EFLT4KDRSTING1 | |
| SCHEMBL3163908 | 0.87 | LMNA (0.53) | LMNANT5ESTING1BCHEABCB1 | |
| SCHEMBL3163915 | 0.87 | LMNA (0.53) | LMNANT5ESTING1BCHEABCB1 | |
| SCHEMBL13970745 | 0.87 | LMNA (0.53) | LMNANT5ESTING1BCHEABCB1 | |
| SCHEMBL8621824 | 0.84 | SLC29A1 (0.46) | LMNANT5ESTING1BCHESLC29A1 | |
| SCHEMBL8621820 | 0.84 | SLC29A1 (0.46) | LMNANT5ESTING1BCHESLC29A1 | |
| SCHEMBL9850267 | 0.83 | LMNA (0.63) | LMNANT5EFLT4KDRABCB1 | |
| SCHEMBL8621079 | 0.82 | SLC29A1 (0.43) | NT5EBCHESLC29A1 | |
| SCHEMBL21367453 | 0.82 | SLC29A1 (0.43) | NT5EBCHESLC29A1 | |
| SCHEMBL8621084 | 0.82 | SLC29A1 (0.43) | NT5EBCHESLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428109-A2 | Deoxyfluoronucleoside process | Bristol-Myers Squibb Company (US) | 1991-05-22 | — | — | EP | disclosed |