Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364756 | 0.89 | GAA (0.65) | TDP1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7717024 | 0.88 | HDAC3 (0.61) | TDP1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7719067 | 0.88 | HDAC3 (0.61) | TDP1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7717055 | 0.88 | HDAC3 (0.61) | TDP1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL4929276 | 0.85 | HDAC1 (0.58) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL4361189 | 0.85 | KDM1A (0.62) | TDP1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL3223491 | 0.83 | KDM1A (0.60) | TDP1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL13416408 | 0.82 | KDM1A (0.68) | TDP1SMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL29721986 | 0.81 | MAPK1 (0.69) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL5536448 | 0.81 | MAPK1 (0.69) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053325-A | 2-hydrogen bond donating group-substituted benzoyl acetanilides | KONICA CORPORATION (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0422505-A1 | Silver halide color photographic light-sensitive material | KONICA CORPORATION (JP) | 1991-04-17 | — | — | EP | disclosed |