SCHEMBL4361189

SCHEMBL4361189

O=C(O)CC(=O)Nc1ccccc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.62
POLB P06746 1/20 0.61
GAA P10253 5/20 0.53
NPC1 O15118 4/20 0.53
TP53 P04637 2/20 0.53
LMNA P02545 1/20 0.53
HTT P42858 1/20 0.53
KMT2A Q03164 6/20 0.53
MEN1 O00255 5/20 0.53
RAB9A P51151 5/20 0.51
MAPT P10636 3/20 0.51
ALDH1A1 P00352 1/20 0.51
HPGD P15428 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HSD17B10 Q99714 1/20 0.51
PKM P14618 1/20 0.51
MMP1 P03956 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13416408 0.90 KDM1A (0.68) KDM1AGAANPC1TP53LMNA
SCHEMBL9850232 0.85 TDP1 (0.61) KDM1APOLBGAANPC1KMT2A
SCHEMBL17993533 0.82 KDM1A (0.70) KDM1AGAANPC1TP53LMNA
SCHEMBL4743115 0.82 KDM1A (0.60) KDM1AGAANPC1TP53LMNA
SCHEMBL2364756 0.82 GAA (0.65) KDM1AGAANPC1HTTKMT2A
SCHEMBL10955276 0.82 KDM1A (0.59) KDM1AGAANPC1TP53LMNA
SCHEMBL29511368 0.81 HPGD (0.67) KDM1AGAALMNAHTTKMT2A
SCHEMBL14817490 0.81 KMT2A (0.65) KDM1AGAANPC1TP53LMNA
SCHEMBL4433540 0.81 HPGD (0.67) KDM1AGAALMNAHTTKMT2A
SCHEMBL7719067 0.80 HDAC3 (0.61) GAANPC1KMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871517-B2 Method of using a control solution and preparing for testing using the same BAYER HEALTHCARE LLC (US) 2014-10-28 US claimed
US-8716024-B2 Control solution for use in testing an electrochemical system BAYER HEALTHCARE LLC (US) 2014-05-06 US claimed
US-20130078724-A1 Control Solution For Use In An Electrochemical System BAYER HEALTHCARE LLC (US) 2013-03-28 US claimed
US-8337691-B2 Control markers for auto-detection of control solution and method of use BAYER HEALTHCARE LLC (US) 2012-12-25 US claimed
WO-2009076302-A1 CONTROL MARKERS FOR AUTO-DETECTION OF CONTROL SOLUTION AND METHODS OF USE BAYER HEALTHCARE LLC (US) 2009-06-18 WO claimed
US-20090148875-A1 Control markers for auto-detection of control solution and method of use ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2009-06-11 US claimed
CN-118765915-A Application of isoniazid and/or hydralazine in preventing and treating wheat stem basal rot 德州学院 2024-10-15 CN disclosed
US-10690614-B2 Method of using an electrochemical test sensor ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2020-06-23 US disclosed
US-20180180565-A1 Method Of Using An Electrochemical Test Sensor BAYER HEALTHCARE LLC 2018-06-28 US disclosed
US-9933385-B2 Method of using an electrochemical test sensor ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2018-04-03 US disclosed
CN-105018506-A Hydrolase of benzoxazolone compound, gene for coding hydrolase and engineering strain containing gene and application thereof UNIV NANJING AGRICULTURAL 2015-11-04 CN disclosed
US-20150008143-A1 Method Of Using An Electrochemical Test Sensor ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2015-01-08 US disclosed
US-8871517-B2 Method of using a control solution and preparing for testing using the same BAYER HEALTHCARE LLC (US) 2014-10-28 US disclosed
US-8716024-B2 Control solution for use in testing an electrochemical system BAYER HEALTHCARE LLC (US) 2014-05-06 US disclosed
US-20130078724-A1 Control Solution For Use In An Electrochemical System BAYER HEALTHCARE LLC (US) 2013-03-28 US disclosed
US-8337691-B2 Control markers for auto-detection of control solution and method of use BAYER HEALTHCARE LLC (US) 2012-12-25 US disclosed
WO-2009076302-A1 CONTROL MARKERS FOR AUTO-DETECTION OF CONTROL SOLUTION AND METHODS OF USE BAYER HEALTHCARE LLC (US) 2009-06-18 WO disclosed
US-20090148875-A1 Control markers for auto-detection of control solution and method of use ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2009-06-11 US disclosed