Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | FDPS | P14324 | 11/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297925 | 0.92 | TSHR (0.39) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL9576868 | 0.90 | TSHR (0.44) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL7445172 | 0.90 | TSHR (0.44) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL9625652 | 0.90 | TSHR (0.37) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL11855953 | 0.86 | SMPD1 (0.31) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL9625884 | 0.86 | TSHR (0.36) | TSHRALDH1A1TDP1THRBSMPD1 | |
| SCHEMBL9625386 | 0.86 | TSHR (0.41) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL9625864 | 0.85 | TSHR (0.33) | TSHRTHRBSMPD1FDPSGGPS1 | |
| SCHEMBL8901964 | 0.85 | TSHR (0.40) | TSHRTDP1THRBSMPD1FDPS | |
| SCHEMBL8039291 | 0.84 | TSHR (0.35) | TSHRALDH1A1TDP1THRBFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444604-A2 | Crosslinking of fluorrubber via crosslinking initiators not forming any methyl- or phenyl-radicals | Elf Atochem Deutschland GmbH (DE) | 1991-09-04 | — | — | EP | disclosed |