Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.50 |
| ▸ | HNF4A | P41235 | 3/20 | 0.50 |
| ▸ | RARA | P10276 | 3/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | RARG | P13631 | 3/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850143 | 0.91 | RXRA (0.53) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6669480 | 0.90 | RXRA (0.45) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6665895 | 0.89 | RXRA (0.44) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL9850251 | 0.87 | RXRA (0.56) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6665724 | 0.86 | RXRA (0.46) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6679884 | 0.83 | RXRA (0.64) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL8461561 | 0.82 | RXRA (0.62) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6668009 | 0.81 | RXRA (0.47) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL9850230 | 0.81 | RXRA (0.42) | RXRAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9850174 | 0.79 | RARB (0.48) | RXRAHNF4ARARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435681-A1 | Chroman esters of phenols and benzoic acids having retinoid-like activity | ALLERGAN, INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006550-A | Skin disorder, arthritis, wound healing agents, dry eye syndrome | ALLERGAN, INC. (US) | 1991-04-09 | — | — | US | disclosed |