Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.68 |
| ▸ | CA4 | P22748 | 2/20 | 0.68 |
| ▸ | CA7 | P43166 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850613 | 0.85 | CA12 (0.66) | CA12CA4CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL9850537 | 0.84 | CA12 (0.64) | CA12CA4CA7CA9CA14 | |
| SCHEMBL11882576 | 0.81 | CA12 (1.00) | CA12CA4CA7CA9CA14 | |
| SCHEMBL9850363 | 0.80 | CA12 (0.70) | CA12CA4CA7CA9CA14 | |
| SCHEMBL3655465 | 0.79 | CA12 (0.74) | CA12CA4CA7CA9CA14 | |
| SCHEMBL9850400 | 0.79 | KDM4E (0.59) | EPHX1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL10244352 | 0.78 | CA12 (0.73) | CA12CA4CA7CA9CA14 | |
| SCHEMBL9850593 | 0.77 | CA12 (0.58) | CA12CA4CA7CA9CA14 | |
| SCHEMBL11283741 | 0.76 | CA12 (0.77) | CA12CA4CA7CA9CA14 | |
| SCHEMBL9850387 | 0.76 | CA12 (0.54) | CA12CA4CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |