Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 1/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9850397 | 0.99 | CA12 (0.57) | CA12CA4CA7CA9CA14 | |
| SCHEMBL21974647 | 0.80 | RAB9A (0.57) | EPHX1MAPTGAAHPGDALDH1A1 | |
| SCHEMBL9850613 | 0.78 | CA12 (0.66) | CA12CA4CA7CA9CA14 | |
| SCHEMBL171696 | 0.78 | KDM4E (0.62) | EPHX1MAPTGAAHPGDLMNA | |
| Hydrochloric Acid SCHEMBL9850537 | 0.77 | CA12 (0.64) | CA12CA4CA7CA9CA14 | |
| SCHEMBL25342805 | 0.77 | KDM4E (0.56) | EPHX1MAPTGAAHPGDLMNA | |
| SCHEMBL6035645 | 0.77 | HSD17B10 (0.60) | CA12CA4CA7CA9CA14 | |
| SCHEMBL25342801 | 0.77 | KDM4E (0.56) | EPHX1MAPTGAAHPGDLMNA | |
| SCHEMBL9850281 | 0.77 | CA12 (0.68) | CA12CA4CA7CA9CA14 | |
| SCHEMBL171258 | 0.76 | EPHX1 (0.60) | EPHX1MAPTGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |