Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.71 |
| ▸ | EBP | Q15125 | 1/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | DRD3 | P35462 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11462886 | 0.88 | SIGMAR1 (0.74) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL10887412 | 0.85 | SIGMAR1 (0.71) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL10887406 | 0.85 | SIGMAR1 (0.71) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL9141946 | 0.85 | SIGMAR1 (0.71) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL11435385 | 0.85 | SIGMAR1 (0.71) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL4454622 | 0.85 | EBP (0.70) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL11927700 | 0.85 | EBP (0.70) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL14146050 | 0.85 | EBP (0.70) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL11927701 | 0.85 | EBP (0.70) | SIGMAR1EBPADORA3CHRM1DRD3 | |
| SCHEMBL4454620 | 0.85 | EBP (0.70) | SIGMAR1EBPADORA3CHRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444706-A2 | Aryl-propyl-amines having antifungal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1991-09-04 | — | — | EP | disclosed |