Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13045462 | 0.84 | CA12 (0.53) | CA12CA14CA4CA7CA9 | |
| Hydrochloric Acid SCHEMBL9850536 | 0.79 | ALDH1A1 (0.70) | CA12CA14CA4CA7CA9 | |
| SCHEMBL13995633 | 0.79 | CA12 (0.54) | CA12CA14CA4CA7CA9 | |
| SCHEMBL11283741 | 0.79 | CA12 (0.77) | CA12CA14CA4CA7CA9 | |
| Hydrochloric Acid SCHEMBL9850443 | 0.78 | ALDH1A1 (0.55) | CA12CA14CA4CA7CA9 | |
| SCHEMBL9850467 | 0.77 | CA12 (0.44) | CA12CA14CA4CA7CA9 | |
| Hydrochloric Acid SCHEMBL4443499 | 0.77 | ALDH1A1 (0.78) | CA12CA14CA4CA7CA9 | |
| SCHEMBL9987427 | 0.76 | CA12 (0.49) | CA12CA14CA4CA7CA9 | |
| SCHEMBL9850321 | 0.75 | MAPT (0.63) | CA12CA14CA4CA7CA9 | |
| SCHEMBL4970631 | 0.74 | CA12 (0.51) | CA12CA14CA4CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |