Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248803 | 0.90 | TDP1 (0.51) | SLC18A3SIGMAR1 | |
| Acetic Acid SCHEMBL11738287 | 0.72 | SLC18A3 (0.44) | SLC18A3 | |
| SCHEMBL28954933 | 0.70 | POLB (0.52) | — | |
| SCHEMBL5152847 | 0.69 | MC4R (0.49) | SLC18A3 | |
| SCHEMBL25136686 | 0.69 | TDP1 (0.50) | — | |
| SCHEMBL19317460 | 0.69 | TDP1 (0.80) | SLC18A3 | |
| SCHEMBL1856334 | 0.69 | TDP1 (0.80) | SLC18A3 | |
| SCHEMBL23043270 | 0.69 | TDP1 (0.80) | SLC18A3 | |
| SCHEMBL5961492 | 0.69 | TDP1 (0.50) | — | |
| SCHEMBL9540610 | 0.69 | TDP1 (0.80) | SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417059-A2 | Bicyclic tetrahydroxylated pyrrolizidines | MONSANTO COMPANY (US) | 1991-03-13 | — | — | EP | claimed |