Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850515 | 0.78 | CA12 (0.51) | TAOK1ALDH1A1HPGDEPHX1MAPT | |
| SCHEMBL9850502 | 0.74 | KMT2A (0.45) | ALDH1A1HPGDEPHX1MAPTKMT2A | |
| SCHEMBL9850454 | 0.73 | CYP2C19 (0.58) | ALDH1A1HPGDANPEPEPHX1MAPT | |
| SCHEMBL11517897 | 0.73 | MEN1 (0.47) | ALDH1A1HPGDKMT2AMEN1KCNJ11 | |
| SCHEMBL3931602 | 0.70 | ANPEP (0.50) | ALDH1A1HPGDANPEPEPHX1MAPT | |
| SCHEMBL18891775 | 0.70 | KCNJ11 (0.42) | ALDH1A1KMT2AMEN1KCNJ11ABCC9 | |
| SCHEMBL9850467 | 0.68 | CA12 (0.44) | ALDH1A1HPGDANPEPCYP1A2KDM4E | |
| SCHEMBL23077764 | 0.67 | CA12 (0.50) | ALDH1A1HPGDANPEPEPHX1MAPT | |
| SCHEMBL776594 | 0.67 | KCNJ11 (0.63) | ALDH1A1HPGDEPHX1MAPTCYP1A2 | |
| SCHEMBL8171726 | 0.66 | NCEH1 (0.44) | ALDH1A1MAPTCYP1A2CYP2C19KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |