Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.63 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.63 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.63 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775262 | 0.91 | EP300 (0.61) | KCNJ11ABCC9ABCC8KCNJ8MAPK1 | |
| SCHEMBL776816 | 0.90 | EP300 (0.64) | KCNJ11ABCC9ABCC8KCNJ8MAPK1 | |
| SCHEMBL778783 | 0.90 | EP300 (0.64) | KCNJ11ABCC9ABCC8KCNJ8MAPK1 | |
| SCHEMBL778848 | 0.87 | MAPK1 (0.51) | KCNJ11ABCC9ABCC8KCNJ8MAPK1 | |
| SCHEMBL30665216 | 0.84 | MAPK1 (0.55) | KCNJ11ABCC9ABCC8KCNJ8MAPK1 | |
| SCHEMBL775301 | 0.83 | SMN1; SMN2 (0.56) | KCNJ11ABCC9ABCC8KCNJ8CYP1A2 | |
| SCHEMBL12608238 | 0.82 | CYP2C19 (0.72) | MAPK1CYP1A2CYP2C19HTTALDH1A1 | |
| SCHEMBL12456328 | 0.82 | CYP2C19 (0.72) | MAPK1CYP1A2CYP2C19HTTALDH1A1 | |
| SCHEMBL14229913 | 0.80 | NCEH1 (0.54) | KCNJ11ABCC9ABCC8KCNJ8MAPK1 | |
| SCHEMBL776746 | 0.79 | LMNA (0.60) | MAPK1EP300ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |