Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850700 | 0.84 | CYP3A4 (0.32) | SLC2A1CYP3A4CYP2D6 | |
| SCHEMBL9850671 | 0.79 | MAPT (0.44) | RAB9AMEN1KMT2AMAPTGAA | |
| SCHEMBL9428488 | 0.79 | SLC2A1 (0.39) | RAB9AALDH1A1MAPTNPC1SLC2A1 | |
| SCHEMBL29004549 | 0.76 | KDM4E (0.40) | KDM4ERAB9APOLBMEN1KMT2A | |
| SCHEMBL9850752 | 0.75 | — | — | |
| SCHEMBL9850739 | 0.74 | CYP3A4 (0.51) | KDM4ERAB9APOLBMEN1KMT2A | |
| SCHEMBL12173063 | 0.74 | CYP3A4 (0.51) | KDM4ERAB9APOLBMEN1KMT2A | |
| SCHEMBL9850826 | 0.74 | CYP3A4 (0.51) | KDM4ERAB9APOLBMEN1KMT2A | |
| SCHEMBL29151239 | 0.73 | MEN1 (0.41) | KDM4ERAB9APOLBMEN1KMT2A | |
| SCHEMBL9850741 | 0.72 | HPGD (0.31) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409634-A2 | Liquid crystal compounds and optically active compounds | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |