Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850566 | 0.85 | NPC1 (0.55) | RAB9ANPC1L3MBTL1POLBKMT2A | |
| SCHEMBL9850383 | 0.81 | KMT2A (0.46) | RAB9ANPC1L3MBTL1KMT2AMEN1 | |
| SCHEMBL9850506 | 0.80 | HTR1A (0.48) | RAB9ANPC1L3MBTL1POLBKMT2A | |
| SCHEMBL9850488 | 0.80 | MAPT (0.54) | RAB9ANPC1L3MBTL1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL9850592 | 0.79 | BCHE (0.52) | RAB9ANPC1L3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9850493 | 0.78 | MEN1 (0.52) | L3MBTL1POLBKMT2AMEN1MAPT | |
| SCHEMBL9850631 | 0.78 | NPC1 (0.55) | RAB9ANPC1L3MBTL1POLBKMT2A | |
| SCHEMBL9850410 | 0.77 | HTR1A (0.62) | RAB9ANPC1L3MBTL1POLBKMT2A | |
| SCHEMBL522650 | 0.76 | MEN1 (0.59) | L3MBTL1POLBKMT2AMEN1MAPT | |
| SCHEMBL9850257 | 0.76 | MEN1 (0.51) | RAB9ANPC1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443862-A1 | Triamine derivatives and their acid-addition salts | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |