SCHEMBL9850834

SCHEMBL9850834

Oc1ccccc1C(Cl)(Cl)c1ccccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TSHR P16473 5/20 0.56
TDP1 Q9NUW8 3/20 0.56
CA2 P00918 5/20 0.47
ALOX15 P16050 3/20 0.47
LMNA P02545 3/20 0.47
HPGD P15428 3/20 0.47
HSD17B10 Q99714 3/20 0.47
CA4 P22748 2/20 0.47
EGFR P00533 2/20 0.47
FYN P06241 2/20 0.47
MMP9 P14780 2/20 0.47
RECQL P46063 2/20 0.47
KDM4E B2RXH2 2/20 0.47
NPC1 O15118 2/20 0.47
MAPT P10636 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CA12 O43570 1/20 0.47
GMNN O75496 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30475078 0.83 TSHR (0.56) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL7190832 0.83 TSHR (0.56) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL27651539 0.81 ALDH1A1 (0.54) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL28067112 0.81 ALDH1A1 (0.54) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL9790802 0.79 ALDH1A1 (0.52) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL9790793 0.79 ALDH1A1 (0.52) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL11355317 0.79 ALDH1A1 (0.65) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL578112 0.77 ALDH1A1 (0.62) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL829757 0.75 ALDH1A1 (0.48) ALDH1A1TSHRTDP1CA2ALOX15
SCHEMBL9472227 0.75 ALDH1A1 (0.48) ALDH1A1TSHRTDP1CA2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4465516-A Asymmetrical diesters of ortho-phosphoric acid useful as corrosion inhibitors SANDOZ LTD. (CH) 1984-08-14 US claimed
CN-102369949-A Scale inhibiting and corrosion mitigating bactericide YINHUI BAI 2012-03-14 CN disclosed
EP-0410213-A1 Microbicidal formulations and their use BAYER AG (DE) 1991-01-30 EP disclosed
US-4142999-A CLEANING AGENTS, ALKOXYLATED ALKYLAMINE AS STABILIZER HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-03-06 US disclosed