Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438858 | 0.80 | CYP1A2 (0.50) | CYP1A2HPGDKDM5APHF8KDM2A | |
| SCHEMBL8392406 | 0.79 | KDM4E (0.50) | CYP1A2HPGDSIGMAR1EPHX1 | |
| SCHEMBL8392716 | 0.79 | KDM4E (0.50) | CYP1A2HPGDSIGMAR1EPHX1 | |
| SCHEMBL19731592 | 0.77 | SIGMAR1 (0.56) | CYP1A2KDM5APHF8KDM2AKDM4C | |
| SCHEMBL12344961 | 0.77 | CYP1A2 (0.54) | CYP1A2HPGDKDM5APHF8KDM2A | |
| SCHEMBL8395918 | 0.77 | KDM4E (0.52) | CYP1A2SIGMAR1EPHX1 | |
| SCHEMBL9668398 | 0.76 | CYP1A2 (0.52) | CYP1A2HPGDKDM5APHF8KDM2A | |
| SCHEMBL24115530 | 0.76 | SIGMAR1 (0.59) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL9253742 | 0.76 | CYP1A2 (0.56) | CYP1A2HPGDKDM5APHF8KDM2A | |
| SCHEMBL9257724 | 0.76 | CYP1A2 (0.56) | CYP1A2HPGDKDM5APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447188-A2 | 7-Oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic diseases | E.R. SQUIBB & SONS, INC. (US) | 1991-09-18 | — | — | EP | disclosed |
| EP-0403090-A1 | 7-oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasopastic disease | E.R. SQUIBB & SONS, INC. (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4977174-A | Anticoagulants, antischemic agents | E. R. SQUIBB & SONS, INC. (US) | 1990-12-11 | — | — | US | disclosed |