Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 18/20 | 0.77 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.75 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554468 | 0.92 | FDPS (0.67) | FDPSGGPS1AGTR1OPRM1PDE3A | |
| SCHEMBL7941507 | 0.91 | FDPS (0.67) | FDPSGGPS1AGTR1OPRM1PDE3A | |
| SCHEMBL9397371 | 0.88 | FDPS (1.00) | FDPSGGPS1SIGMAR1AGTR1OPRM1 | |
| SCHEMBL6222753 | 0.88 | FDPS (1.00) | FDPSGGPS1SIGMAR1AGTR1OPRM1 | |
| SCHEMBL9394781 | 0.88 | FDPS (1.00) | FDPSGGPS1SIGMAR1AGTR1OPRM1 | |
| SCHEMBL9730804 | 0.87 | FDPS (0.97) | FDPSGGPS1SIGMAR1AGTR1OPRM1 | |
| SCHEMBL9394634 | 0.87 | FDPS (1.00) | FDPSGGPS1SIGMAR1AGTR1OPRM1 | |
| SCHEMBL6224119 | 0.85 | FDPS (1.00) | FDPSGGPS1AGTR1OPRM1PDE3A | |
| SCHEMBL9554186 | 0.84 | FDPS (0.65) | FDPSGGPS1 | |
| SCHEMBL9397452 | 0.80 | FDPS (0.84) | FDPSGGPS1SIGMAR1AGTR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407344-A2 | Pharmaceutical preparation for topical application | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | claimed |